Forward-Deployed AI Engineer · AI Systems Operator

Ryan
Bonelli

AI integration that compounds. Multi-model systems and autonomous agents, deployed across every department — engineered by the operator who has run the work, not adjacent to it.

How I work → Send a brief →
Currently accepting engagements · 48-hour reply

Services · The Practice

Inside the work,
not adjacent.

4–6×Productivity Multiplication

Most AI adoption looks the same: a tool on every desk, a pilot every quarter, nothing that compounds. The practice does the opposite. Multi-model orchestration, autonomous agents, and workflow automation — deployed as one operating layer, engineered into the work your team already does, built to compound across functions instead of fragmenting across tools.

The differentiator is reach. I've built and run companies across every department I now deploy into — sales, marketing, sourcing, logistics, manufacturing, engineering, customer operations, documentation, investor relations, and executive ops. The AI lands inside the actual work because I've done the actual work.

Engagement Model · Five Phases

01 · Map
How work actually moves

A structured review of how work moves through your business — by department, function, and hand-off. We surface where time is leaking, where quality is degrading, and where AI can carry real load.

02 · Prioritize
The few that compound

Not every workflow is worth automating. We isolate the few that compound — where AI delivers outsized leverage on speed, quality, or decision-making. Ranked by operational ROI, not theoretical capability.

03 · Build
Production, not pilots

Code-level engineering. Multi-model orchestration, autonomous agents, and workflow automation built into your existing stack. Production systems your team owns — not demos, not pilots, not vendor lock-in.

04 · Enable
Capability stays in-house

Your people are the multiplier. I train them on the methodology, the systems, and the operating discipline to run AI-augmented work at scale. The capability stays in-house when I leave. It has to.

05 · Codify
Institutional ownership

Documentation, governance, and operating standards so the gains compound. AI integration becomes institutional capability — not a single-person dependency, not a one-off project, not something that breaks when you leave the room.

What changes

Speed of execution. Quality of output. Depth of decision-making. Throughput of the entire business.

Functional Reach · Across Eleven Departments

Sales Marketing Administration Sourcing Logistics Manufacturing Engineering Customer Comms Documentation Investor Relations Executive Ops

Strategy, engineering, deployment, and team enablement — one engagement, end-to-end. Selective by design.

Discuss an engagement →

Build Studio · Software Team

Led by Ryan Bonelli

Houtos
Labs.

When the work needs more than one person, my team takes over. Houtos Labs is a senior-only build studio I lead — engineers and designers shipping custom software for operating companies. Apps, advanced web platforms, and full software-system integrations: built end-to-end, handed off production-ready, owned by your team from day one.

Not an agency. Not a marketplace. A small team that builds the way operators want software built — opinionated, fast, accountable to the result. Available as a standalone engagement, or alongside the AI integration practice when you need both.

01 · Build
Applications

Native iOS and Android, cross-platform mobile, desktop. MVP through production scale — designed for retention, engineered to last past the launch.

React NativeSwiftKotlinTauri
02 · Platform
Advanced Web Platforms

Real-time data, complex state, enterprise architecture. SaaS products, customer portals, internal tools, operator dashboards — built to perform under real load, not just demo well.

ReactNext.jsNodePostgresWebSocket
03 · Integrate
Systems Integration

Custom integrations across your existing stack — databases, CRMs, ERPs, payment rails, internal tooling. Making the systems that don't talk, talk — so the business actually moves.

RESTGraphQLWebhooksETLCloud

Design, engineering, deployment, ongoing support — under one roof, by a team that ships. Available for full custom builds and longer-term partnerships.

Engage Houtos Labs →

About

Forward-Deployed AI Engineer.
AI Systems Operator.
Two-decade founder.

Day job: Chief Operating Officer across two active companies in advanced manufacturing and life sciences, and Co-Founder of Peregrine Precision Systems — a platform spanning process equipment, ingredient production, and pharmaceutical research.

Practice: hands-on AI engineering for operating companies. Multi-model orchestration, autonomous agents, and workflow automation — deployed as a single operating layer, owned by the team. I write code when needed. The real advantage is the operating method, and the operator who has run the work it gets deployed into.

4–6×
Workflow Multiplier
11
Departments Covered
11
Platforms Self-Built
2001
Career Start
LocationHappy Valley, OR
For hireAI integration · Custom builds
StudioHoutos Labs
Current rolesCOO · Co-Founder
ResearchMcMaster · Magolan Lab
AdvisoryAI SaaS · Decentralized tech
Dev focusAI agents · Web3 · Quant
Team led8-person executive team
Contactryan_bonelli@yahoo.com
Ryan Bonelli portrait
Happy Valley, OR
// independent development stack
contracts ERC-4337 · ERC-721 · ERC-1155
chains Base L2 · Ethereum mainnet
oracles Chainlink · Pyth · Uniswap TWAP
backend Python · Node · REST · WebSocket
frontend React · Vanilla JS
AI LLM · RAG · fine-tuning
ops GMP · cGMP · ASME/UL · P&L
4–6×
Workflow Multiplier
0
Departments Covered
0
Years in Operations
0
Platforms Self-Built
Currently Updated this week
BuildingKaizen multi-intelligence trading desk — extending the agent decision layer with on-chain execution telemetry.
EngineeringA second iteration of Content Engine — pushing the 70–90% time compression deeper into design and review stages.
OperatingDecimal Engineered Systems ship cadence and Peregrine Precision Systems portfolio coordination.
ReadingOperating-method literature on multi-agent orchestration and the failure modes of human-AI handoff at scale.

Pharmaceutical Research

Advanced compound synthesis
toward clinical application.

Through Peregrine Precision Systems, I co-founded NatSyn (Naturally Synthetic Inc.) — a joint venture with the Magolan Laboratory at McMaster University. NatSyn synthesizes rare, naturally occurring plant-derived compounds that cannot be cost-effectively sourced from biomass at commercial scale.

Using patent-pending chemistry, the lab produces novel active pharmaceutical ingredients at clinical purity standards for the global research and pharmaceutical communities. Three compound programs are currently positioned for potential Phase I human clinical trials, developed in collaboration with academic and medical researchers.

Featured In
Yahoo Finance McMaster University Magolan Laboratory
Published Coverage
Yahoo Finance · Sep 2021
Peregrine Precision Systems & McMaster University Launch Joint Research Venture
Yahoo Finance · Nov 2021
PPS Ramps Production of Novel Synthetic APIs — Scales from 1g to 100g in Single-Day Process
Yahoo Finance · Mar 2024
Mandesh Dosanjh Joins Peregrine Precision Systems as Chairman
3
Clinical Trial Candidates
Three compound programs under active development with medical researchers, positioned for potential Phase I human clinical trial progression.
>99%
API Synthesis Purity
Synthesis achieved at greater than 99% purity using patent-pending chemistry, meeting Active Pharmaceutical Ingredient grade standards.
100g
Single-Day Batch Capacity
Production scaled significantly within months of launch. Multi-kilo commercial scale-up underway at the Oregon facility.
McMaster
University Partner
Sponsored Research Contract with the Magolan Lab — the Boris Family Endowed Chair of Drug Discovery at McMaster University.

Portfolio

Platforms & web properties
built independently.

Designed, architected, and coded personally — outside my professional roles. Each built from scratch, no contractors, no agencies.

Educational Platform · In Development EdifyEUD Building learning experiences with multi-model AI
20% Complete · In active development
Dev · 20%
EducationEdTechAISaaS
EdifyEUD
edifyeud.com

Educational platform under active development. Building structured learning experiences powered by multi-model AI, designed for self-directed learners and instructional workflows. Currently 20% through build — architecture, core learning engine, and content pipeline in place.

ReactNodeLLMRAGMulti-Agent
Peregrine.Technology dashboard
Visit site →
Live
AISaaSInvestor RelationsB2B
Peregrine.Technology
peregrine.technology

Portfolio company stakeholder dashboard and investor communications platform. AI-assisted update generation, automated reporting cadence, and a centralized layer for cross-portfolio communication. Built independently to operationalize my own investor relations practice across PPS.

ReactNodeLLMPythonPostgres
Multi-Model AI · Productivity Content Engine 70–90% time compression on structured production
In production use
Live
AIMulti-ModelProductivityEducation
Content Engine
Internal · Production

Semi-autonomous platform for developing educational presentations and structured long-form content. Multi-model orchestration coordinates research, drafting, design, and review — compressing a 30–60 hour production cycle into 4–8 hours. Measured time reduction: 70–90% on real output.

PythonLLMRAGMulti-AgentNode
Kaizen trading engine dashboard
Visit site →
Live
AIFintechQuantWeb3
Kaizen
kaizenxyz.xyz

A financial quant desk built on a multi-intelligence trading system. Walk-forward strategy validation, information-coefficient analysis, on-chain execution with MEV and slippage protection, and a multi-agent decision layer orchestrating signal, sizing, and execution across Base L2.

PythonSolidityBase L2Multi-AgentChainlink
Based Guardians command center
Visit site →
Live
Web3NFTBase L2Gaming
Based Guardians
basedguardians.xyz

Full-scale Web3 gaming platform on Base L2 — play-to-earn mechanics, custom smart contracts, NFT minting engine, transactional marketplace, live data dashboards, and on-chain leaderboards. Built entirely from scratch.

SolidityReactBase L2ERC-4337Node
Opsona AI-native operations platform
Visit site →
Live
AISaaSRegulated Mfg
Opsona.ai
opsona.ai

AI-native operations platform for regulated manufacturing — compliance automation, SOPs, training management, and quality systems for FDA-regulated facilities. Website and Phase One built independently.

ReactPythonLLMRAGNode
Decimal Engineered Systems platform
Visit site →
In Progress
E-commerceAIB2BManufacturing
Decimal Engineered
decimal.supply

Custom B2B platform for precision process equipment — AI education layer, e-commerce marketplace, authenticated customer portal with live machine data dashboards. Built independently from the company I operate.

ReactPythonLLMNodeREST API
MRX Manufacturing precision engineered
Visit site →
Live
ManufacturingB2BIndustrialOregon
MRX Manufacturing
mrxmfg.com

Oregon-engineered precision manufacturing platform — high-density liquid cooling systems for AI data centers and semiconductor fabs, plus ASME-compliant process equipment for pharma, food, and defense. Custom storefront, capabilities matrix, and quote engine, all built from scratch.

ReactNodeCustom CMS
Non-Custodial DeFi · Base L2 GoldBUG ERC-4337 account abstraction · Real-asset accumulation
In Development
Dev
Web3DeFiAlgo TradingBase L2
GoldBUG / NiffLer
Active development

Non-custodial fintech platform on Base L2. ERC-4337 account abstraction, multi-source oracle consensus, algorithmic trading engine, and real-asset accumulation mechanics. Self-architected.

SolidityERC-4337PythonChainlinkPyth
LabGear Supply e-commerce storefront
Visit site →
Live
E-commerceB2BLab SupplyScientific
LabGear Supply
labgear.supply

B2B e-commerce platform serving processing labs with premium scientific consumables and equipment. Distribution partnerships with leading instrument manufacturers including Huber, Heidolph, Julabo, Büchi, and Swagelok. Full storefront, inventory, and order management — built independently.

E-commerceInventoryPaymentsDistribution
E-Commerce · Multi-Country Monster Gardens $0 → $11M · 4-country distribution · 85K subscribers
monstergardens.com →
Live
E-commerceRetailDistribution
Monster Gardens
monstergardens.com

One of the first large-scale e-commerce operations in its category — built from the ground up. Grew to multi-million dollar revenue across four countries, with a digital education channel that reached 85K subscribers.

E-commerceERPCRMYouTube

Ventures

Companies founded
and operated.

Current · Process Equipment
Decimal Engineered Systems
Chief Operating Officer · 2019 – Present
US-based manufacturer of certified, GMP-compliant process equipment serving pharmaceutical, food, and regulated industries. Full production lifecycle oversight — engineering through customer delivery — with a North American service organization. A subsidiary of Peregrine Precision Systems.
Current · Pharmaceutical R&D
Naturally Synthetic (NatSyn)
Co-Founder via PPS · Active
Joint-venture research lab with McMaster University synthesizing novel APIs at pharmaceutical purity. Three programs approaching clinical trial candidacy.
Current · Platform Holding
Peregrine Precision Systems
COO & Co-Founder · 2019 – Present
Parent company overseeing Decimal, ingredient manufacturing operations, and NatSyn. Strategy, IP management, and commercialization across the portfolio.
Prior · Ingredient Manufacturing
Polar (PPS Division)
COO · Active
GMP ingredient manufacturing for food and pharmaceutical applications. Contributed to significant production output increases and regulatory approvals including novel food designation in the EU.
EU novel food approval
Prior · E-commerce & Retail
Monster Gardens / SPW Inc.
CEO & Co-Founder · 2010 – 2016
Built a large-scale e-commerce and retail operation from the ground up — multi-million dollar revenue, thousands of product lines, four-country distribution, and an 85K-subscriber digital education channel.
4 countries · 85K subscribers
Current · Fintech
GoldBUG
Founder · Active
Independent fintech venture on Base L2. Non-custodial architecture, algorithmic trading infrastructure, and real-asset accumulation in tokenized assets. Self-architected and developed.

Career History

Background &
experience.

2025
Commercialization Advisor
Opsona · 2025 – Present
Leading commercialization for AI-driven operations software for regulated manufacturing — translating technical capabilities into market-ready offerings and go-to-market strategy.
2022
Lead Advisor
Houtos Labs · 2022 – 2025
Product strategy, commercialization, and ecosystem design for decentralized technology initiatives. Translated complex technical concepts into user-facing products and business models.
2019
COO & Co-Founder — Peregrine Precision Systems
Decimal · NatSyn · Polar · 2019 – Present
Leading cross-functional operations across process equipment manufacturing, pharmaceutical R&D, and ingredient production. 8-person executive team, shared P&L with CEO.
2016
Chief Executive Officer
Holistic Research · 2016 – 2019
Led a California-based research and production business from concept through commercial development. Managed design, engineering, construction, and investor relations across multiple project sites.
2013
President
Commercial Supply Company · 2013 – 2016
Led a commercial supply operation through a period of significant industry growth. Business development, key account management, and market positioning.
2010
CEO & Co-Founder — Monster Gardens / SPW Inc.
2010 – 2016
Built two companies from scratch to multi-million dollar revenue. Digital education channel reaching 85K subscribers. Four-country distribution, thousands of SKUs, ERP and CRM implementation at scale.
2004
Account Executive
American Brokers Conduit · 2004 – 2010
Grew a regional wholesale lending territory from the ground up — 15 to 180+ active broker relationships in Northern California.
2001
Real Estate Finance
Temple Inland Mortgage · 2001 – 2004
Early-career foundation in financial analysis, portfolio evaluation, and structured lending.

Professional Background

Operations,
commercialization,
and growth.

Over two decades leading companies across advanced manufacturing, regulated process technologies, pharmaceutical research, financial services, and technology. Consistent track record of building operating platforms, scaling revenue, and translating complex technical capabilities into commercial results.

Full CV

Available upon request. Reach out directly and I'll respond promptly.

Request CV →
Served as COO of Decimal Engineered Systems, supporting the launch of seven machine technologies and significant revenue growth from 2019 to present.
Co-founded Naturally Synthetic Inc. with McMaster University — three compound programs now approaching Phase I clinical trial candidacy.
Built an e-commerce and retail operation from zero to multi-million dollar revenue across four countries with a digital audience of 85K.
Led pharmaceutical ingredient manufacturing operations, achieving significant output increases and international regulatory approvals.
Independently built eleven web properties and platforms spanning AI SaaS, education, Web3, fintech, lab and industrial e-commerce, and B2B manufacturing — no contractors, no agencies.
Grew a wholesale financial services territory from 15 to 180+ active accounts across Northern California.

Writing & Practice

Perspectives on
industry & technology.

Operations
GMP Compliance in Advanced Manufacturing: A Practical Framework

Drawing on operational experience across regulated equipment manufacturing and ingredient production — a practitioner's guide to building repeatable GMP-compliant systems at scale.

Request a copy →
Technology
Non-Custodial DeFi Architecture: Building Without Counterparty Risk

An exploration of ERC-4337 Account Abstraction, oracle consensus design, and the architecture of autonomous financial systems that eliminate centralized key exposure.

Request a copy →
Pharma R&D
Synthetic API Production: Scaling Rare Compounds from Bench to Commercial

Documenting the operational and scientific pathway from academic research partnership to pharmaceutical-grade API synthesis at commercial scale — lessons from NatSyn's launch.

Request a copy →

These papers represent applied thinking from direct operational and development experience. Reach out to discuss any of the topics or to request copies.

Contact

Engage
directly.

For operators, founders, and investors with substantive work in AI integration, custom software, or operational transformation. Send a brief — every reply comes from me, not a gatekeeper.

Available · Typical reply within 48 hours · Happy Valley, OR
Email
ryan_bonelli@yahoo.com
LinkedIn
ryan-bonelli-8a554251
Full CV
Available on request